What does Burkholderia cepacia do to your body?
B cepacia ordinarily is not a pathogen in the ambulatory setting, but it may colonize and/or infect the respiratory tract of patients with cystic fibrosis or bronchiectasis. B cepacia also may cause central venous catheter–related infections in patients with cancer and in those on hemodialysis.
Is Burkholderia cepacia serious?
Most people aren't susceptible to a B. cepacia infection. Some are, though, and in their cases, these bacteria often infect the lungs. This leads to a severe form of pneumonia.
What is the treatment for Burkholderia cepacia?
Infections due to Bcc can be challenging to manage, as Bcc is intrinsically resistant to a number of commonly used antibiotics. Trimethoprim-sulfamethoxazole (TMP-SMX) and ceftazidime are considered first-line options for Bcc infections (1).
Can you get rid of Burkholderia cepacia?
Thus, eradication of BCC can be achieved using a combination of inhaled and oral medication, without intravenous antibiotics. This is of relevance as intravenous tobramycin can lead to systemic toxicity, such as ototoxicity and nephrotoxicity, which is uncommon in inhalation therapy.
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